Proceedings of MATSUS Fall 2023 Conference (MATSUSFall23)
DOI: https://doi.org/10.29363/nanoge.matsus.2023.260
Publication date: 18th July 2023
Understanding and modulating neural networks requires high-resolution acquisition of neural activity over time, real-time analysis, and minimally invasive stimulation methods with high specificity. Such procedures are particularly needed for treatment of sensory disfunction (e.g. hearing loss), and certain neurological diseases (e.g. epilepsy). The lack of soft, biocompatible, hybrid and smart neural interfaces hinders our capacity to study complex neural dynamics and efficiently apply responsive neuromodulation therapy. Here, I am presenting the vision of Neural Waves lab towards designing and developing materials and novel fully implantable, contained and responsive neural interfaces that will allow long-term acquisition and closed-loop manipulation of neural circuits with high spatiotemporal resolution over extended period of time to reveal neural dynamics in different neurological pathways and alleviate disfunctions and diseases. I will cover our studies on i) creating artificial basilar membrane based on acousto-sensitive ion-based transistors and soft electronics, ii) innovating electroencephalography interfaces, and iii) utilizing organic perforated multielectrode arrays to investigate the effect of photopharmacological interventions on Cortical Seizures.