New Models for In Vivo Fabrication and Actuation of Bioelectronic Interfaces

Claudia Tortiglione^a, Giuseppina Tommasini^a^,^b, Gwennaël Dufil^c, Francesca Di Maria^d, Mattia Zangoli^d, Marika Iencharelli^a, Mariarosaria De Simone^a, Angela Tino^a, Maria Moros^b, Eleni Stavrinidou^c

^a1Istituto di Scienze Applicate e Sistemi Intelligenti “E. Caianiello”, Consiglio Nazionale delle Ricerche, Via Campi Flegrei 34, 80078 Pozzuoli, Italy

^bInstituto de Nanociencia y Materiales de Aragón (INMA) C/Mariano Esquillor s/n, 50018 Zaragoza, Spain

^cLaboratory of Organic Electronics, Department of Science and Technology, Linkoping University, SE-60174, Norrkoping, Sweden.

^dIstituto per la Sintesi Organica e Fotoreattività, Consiglio Nazionale delle Ricerche, Via Piero Gobetti, 101, 40129 Bologna, Italy

Proceedings of Organic Bioelectronics Conference 2022 (OBe2022)

Online, Spain, 2022 February 8th - 9th

Organizers: Christopher Proctor, Maria Asplund and Mary Donahue

Contributed talk, Claudia Tortiglione, presentation 013
DOI: https://doi.org/10.29363/nanoge.obe.2022.013
Publication date: 14th January 2022

The unmatchable capability of living cells to fabricate complex structure starting from simple building blocks offers new paradigms to seamlessly integrate new electronic structures into the living matter, creating new hybrid devices. We exploited this potential in a simple tissue-like organism, the freshwater polyp Hydra vulgaris, and here we provide an overview of recent and on-going results obtained with this model together with our methodological approaches ranging from behavioural to optical, spectroscopical, and electrical characterization. By simple exposure to conjugated oligomers we show the capability of Hydra to fabricate new electronically conducting and electrochemically active microstructures in specific cell types [1]. In another case, fluorescent and conductive microfibers embedded into the tentacle tissues were produced starting from oligothiophene compounds, showing the feasibility to use these organisms as biofactories to fabricate and to test novel bioelectronic interface [2]. Tissues with integrated biocompatible electronics, manufactured in vivo in localized regions, may inspire new devices to manipulate biological functions by adding or augmenting conductivity in physiological or pathological contexts with spatiotemporal control, paving the way to new bioengineering concepts.

References

[1] G. Tommasini, G. Dufil, F. Fardella, X. Strakosas, E. Fergola, T. Abrahamsson, D. Bliman, R. Olsson, M. Berggren, A. Tino, E. Stavrinidou, C. Tortiglione, Seamless integration of bioelectronic interface in an animal model via in vivo polymerization of conjugated oligomers, Bioactive Materials 10 (2022) 107-116.

[2] M. Moros, F. Di Maria, P. Dardano, G. Tommasini, H. Castillo-Michel, A. Kovtun, M. Zangoli, M. Blasio, L. De Stefano, A. Tino, G. Barbarella, C. Tortiglione, In Vivo Bioengineering of Fluorescent Conductive Protein-Dye Microfibers, iScience 23(4) (2020) 101022.

nanoGe is a prestigious brand of successful science conferences that are developed along the year in different areas of the world since 2009. Our worldwide conferences cover cutting-edge materials topics like perovskite solar cells, photovoltaics, optoelectronics, solar fuel conversion, surface science, catalysis and two-dimensional materials, among many others.

MATSUS

Previously nanoGe Spring Meeting (NSM) and nanoGe Fall Meeting (NFM), MATSUS is a multiple symposia conference focused on a broad set of topics of advanced materials preparation, their fundamental properties, and their applications, in fields such as renewable energy, photovoltaics, lighting, semiconductor quantum dots, 2-D materials synthesis, charge carriers dynamics, microscopy and spectroscopy semiconductors fundamentals, etc.

International Conference on Hybrid and Organic Photovoltaics

International Conference on Hybrid and Organic Photovoltaics (HOPV) is celebrated yearly in May. The main topics are the development, function and modeling of materials and devices for hybrid and organic solar cells. The field is now dominated by perovskite solar cells but also other hybrid technologies, as organic solar cells, quantum dot solar cells, and dye-sensitized solar cells and their integration into devices for photoelectrochemical solar fuel production.

Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics

The main topics of the Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics (IPEROP) are discussed every year in Asia-Pacific for gathering the recent advances in the fields of material preparation, modeling and fabrication of perovskite and hybrid and organic materials. Photovoltaic devices are analyzed from fundamental physics and materials properties to a broad set of applications. The conference also covers the developments of perovskite optoelectronics, including light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.

International Conference on Perovskite Thin Film Photovoltaics Perovskite Photonics and Optoelectronics

The International Conference on Perovskite Thin Film Photovoltaics Perovskite Photonics and Optoelectronics (NIPHO) is the best place to hear the latest developments in perovskite solar cells as well as on recent advances in the fields of perovskite light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.