Proceedings of MATSUS23 & Sustainable Technology Forum València (STECH23) (MATSUS23)
DOI: https://doi.org/10.29363/nanoge.matsus.2023.191
Publication date: 22nd December 2022
The pulmonary administration of nanomedicines such as viral vaccines is a promising delivery route because it is direct, noninvasive, and it can be used for both systemic delivery and lung targeting. However, the same mechanisms that protect us from pathogens entering via the inhalation route lead to the rapid elimination or degradation of nanomedicines. Most nanomedicines designed for pulmonary administration do not reach clinical practice and this is reflected in the low number of newly approved inhalation drugs.[1] This reality contrasts with the increase in lung diseases due to global ageing and new infectious diseases.[2] Since one of the advantages of pulmonary administration is the direct targeting of the lung, the challenges of improving this route of administration are worthy of being addressed towards overcoming unmet clinical needs. In this context, we will demonstrate that it will be key to study and understand the nano-bio interaction with lung barriers to design better drug nanovectors. To this end, we will give examples of how multifunctional nanoparticles capable of encapsulating drugs and being labeled with contrast agents to perform multiscale studies will be an essential tool to characterize these interactions.[3] We will provide examples of how different coating agents determine lung retention time, clearance by alveolar macrophages, penetration into the lung, etc. Finally, we will show how this may impact the therapeutic efficiency of some of these nanomedicines.
SCR is supported by the Ministerio de Ciencia e Innovación (PID2019-106139RA-100 and RYC2020-030241-I). JRC is funded by MCIN/AEI/10.13039/5011000011033, "ERDF A way of making Europe" (PID2021-123238OB-I00), La Caixa Foundation (HR20-00075) and from the Spanish Fundación contra la Hipertensión Pulmonar.
nanoGe is a prestigious brand of successful science conferences that are developed along the year in different areas of the world since 2009. Our worldwide conferences cover cutting-edge materials topics like perovskite solar cells, photovoltaics, optoelectronics, solar fuel conversion, surface science, catalysis and two-dimensional materials, among many others.
Previously nanoGe Spring Meeting (NSM) and nanoGe Fall Meeting (NFM), MATSUS is a multiple symposia conference focused on a broad set of topics of advanced materials preparation, their fundamental properties, and their applications, in fields such as renewable energy, photovoltaics, lighting, semiconductor quantum dots, 2-D materials synthesis, charge carriers dynamics, microscopy and spectroscopy semiconductors fundamentals, etc.
International Conference on Hybrid and Organic Photovoltaics
International Conference on Hybrid and Organic Photovoltaics (HOPV) is celebrated yearly in May. The main topics are the development, function and modeling of materials and devices for hybrid and organic solar cells. The field is now dominated by perovskite solar cells but also other hybrid technologies, as organic solar cells, quantum dot solar cells, and dye-sensitized solar cells and their integration into devices for photoelectrochemical solar fuel production.
Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics
The main topics of the Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics (IPEROP) are discussed every year in Asia-Pacific for gathering the recent advances in the fields of material preparation, modeling and fabrication of perovskite and hybrid and organic materials. Photovoltaic devices are analyzed from fundamental physics and materials properties to a broad set of applications. The conference also covers the developments of perovskite optoelectronics, including light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.
The International Conference on Perovskite Thin Film Photovoltaics Perovskite Photonics and Optoelectronics (NIPHO) is the best place to hear the latest developments in perovskite solar cells as well as on recent advances in the fields of perovskite light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.