DOI: https://doi.org/10.29363/nanoge.liv-act.2022.006
Publication date: 8th September 2022
Implantable neural prostheses are devices exploited to recover impaired or lost functions, such as vision. In this talk I will present our group effort to develop novel visual prostheses. I will cover aspects spanning from materials, to manufacturing methods and preclinical validation. In particular, I will focus on wireless solutions for stimulation.
A common design constraint in neural implants is the presence of cables connecting the electrode-tissue interface to implantable electronic units. The presence of wires and connectors is a significant disadvantage for neural prostheses. They are weak points often leading to failure, they exert mechanical forces and tractions on the implant and the tissue, and they might lead to post-surgical complications, such as infection. Also, the use of implantable electronic units is another disadvantage due to constraints in power consumption, heat generation, and high risk of failure in a wet environment due to leakage. In neurotechnology, truly wireless electrodes are highly desirable.
POLYRETINA is a wireless retinal prosthesis allowing wide-field and high-resolution stimulation of the retina. First, I will describe our recent results related to POLYRETINA testing. Then, I will discuss how materials and solutions adopted for POLYRETINA are now applied to new devices for artificial vision and other applications.