DOI: https://doi.org/10.29363/nanoge.eimc.2021.018
Publication date: 5th July 2021
Capillary-driven flow microfluidics offers the ability of loading samples into microchannels without the requirement for external pumping mechanisms. Microfluidics devices can be coated with specific reagents and a simple dipping into a fluid sample could trigger a reaction in between reagents and analytes of interest. There is a great potential to explore capillary-driven flow microfluidics and utilize it for point-of-care (POC) diagnostics e.g. for the prevention of antimicrobial resistance (AMR) in healthcare by loading bacterial/pathogenic samples into microchannels, incubating and reading the results near the patient’s bedside [1]. Several such devices have been developed for detection of biomarkers and AMR testing [1-3] along with smartphone detections which offer an alternative approach for portable point-of-need imaging requirements [4]. However, bacterial sample loading into microchannels could be challenging because of the surface properties of the microchannels and clogging of samples at the inlets. Recently, highly branched poly(N-isopropyl acrylamide) incorporating Nile red has been shown to provide a fluorescence signal upon binding to bacteria [5]. This paper showcases a capillary-driven flow microfluidics device (Chip-and-Dip) for loading of bacterial/pathogenic samples into microchannels for antimicrobial testing. This device offers the capability of capturing cells into microchannels that can be further treated with reagents to generate a colorimetric/fluorescent signal. The Chip-and-Dip device, fabricated with inexpensive materials and coated with these reagents, works by simply dipping the reagents-coated microfluidics chip into a sample. Here, we show a successful coating of microchannels with fluorescently labelled polymer and loading of Enterococcus Faecalis spiked in milk samples.
We thank the UKRI Economic and Research Council UK (ES/S000208/1) for funding. This research was performed as part of the DOSA Project (Diagnostics for One Health and User Driven Solutions for AMR).
nanoGe is a prestigious brand of successful science conferences that are developed along the year in different areas of the world since 2009. Our worldwide conferences cover cutting-edge materials topics like perovskite solar cells, photovoltaics, optoelectronics, solar fuel conversion, surface science, catalysis and two-dimensional materials, among many others.
Previously nanoGe Spring Meeting (NSM) and nanoGe Fall Meeting (NFM), MATSUS is a multiple symposia conference focused on a broad set of topics of advanced materials preparation, their fundamental properties, and their applications, in fields such as renewable energy, photovoltaics, lighting, semiconductor quantum dots, 2-D materials synthesis, charge carriers dynamics, microscopy and spectroscopy semiconductors fundamentals, etc.
International Conference on Hybrid and Organic Photovoltaics
International Conference on Hybrid and Organic Photovoltaics (HOPV) is celebrated yearly in May. The main topics are the development, function and modeling of materials and devices for hybrid and organic solar cells. The field is now dominated by perovskite solar cells but also other hybrid technologies, as organic solar cells, quantum dot solar cells, and dye-sensitized solar cells and their integration into devices for photoelectrochemical solar fuel production.
Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics
The main topics of the Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics (IPEROP) are discussed every year in Asia-Pacific for gathering the recent advances in the fields of material preparation, modeling and fabrication of perovskite and hybrid and organic materials. Photovoltaic devices are analyzed from fundamental physics and materials properties to a broad set of applications. The conference also covers the developments of perovskite optoelectronics, including light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.
The International Conference on Perovskite Thin Film Photovoltaics Perovskite Photonics and Optoelectronics (NIPHO) is the best place to hear the latest developments in perovskite solar cells as well as on recent advances in the fields of perovskite light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.