Publication date: 28th June 2024
Treatment of glioblastoma multiforme (GBM) is highly challenging, with current treatments—surgery, chemotherapy, and radiotherapy—yielding a median survival of just ~15 months. The blood-brain barrier (BBB), a semipermeable membrane, complicates drug delivery by blocking potent chemotherapeutic agents from reaching the tumor. This barrier, along with other factors, necessitates innovative approaches to brain cancer treatment. Iontronic pumps (IPs) have emerged as a promising solution. These devices use an ion exchange membrane to precisely control drug release, potentially overcoming the BBB's limitations.
After encouraging results from previous in vitro and in vivo studies, we have now established the operation of IPs in a rat brain tumor model. Utilizing a semi-wireless, Bluetooth-controlled setup, we aim to conduct long-term studies on awake rats. We induce brain tumor growth via a catheter system, through which our device is then inserted for operation. To assess the efficacy within the tissue, we have established protocols to evaluate tumor size, molecular expression of different markers, and pharmacokinetic drug distribution. These experiments aim to evaluate the efficacy of continuous drug dosing in targeting difficult-to-treat tumors over extended periods, taking the chemotherapeutic potential of IPs to the next level.
nanoGe is a prestigious brand of successful science conferences that are developed along the year in different areas of the world since 2009. Our worldwide conferences cover cutting-edge materials topics like perovskite solar cells, photovoltaics, optoelectronics, solar fuel conversion, surface science, catalysis and two-dimensional materials, among many others.
Previously nanoGe Spring Meeting (NSM) and nanoGe Fall Meeting (NFM), MATSUS is a multiple symposia conference focused on a broad set of topics of advanced materials preparation, their fundamental properties, and their applications, in fields such as renewable energy, photovoltaics, lighting, semiconductor quantum dots, 2-D materials synthesis, charge carriers dynamics, microscopy and spectroscopy semiconductors fundamentals, etc.
International Conference on Hybrid and Organic Photovoltaics
International Conference on Hybrid and Organic Photovoltaics (HOPV) is celebrated yearly in May. The main topics are the development, function and modeling of materials and devices for hybrid and organic solar cells. The field is now dominated by perovskite solar cells but also other hybrid technologies, as organic solar cells, quantum dot solar cells, and dye-sensitized solar cells and their integration into devices for photoelectrochemical solar fuel production.
Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics
The main topics of the Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics (IPEROP) are discussed every year in Asia-Pacific for gathering the recent advances in the fields of material preparation, modeling and fabrication of perovskite and hybrid and organic materials. Photovoltaic devices are analyzed from fundamental physics and materials properties to a broad set of applications. The conference also covers the developments of perovskite optoelectronics, including light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.
The International Conference on Perovskite Thin Film Photovoltaics Perovskite Photonics and Optoelectronics (NIPHO) is the best place to hear the latest developments in perovskite solar cells as well as on recent advances in the fields of perovskite light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.