Publication date: 28th June 2024
Many cancer treatments face challenges due to inefficient delivery and systemic toxicity. Our solution involves utilizing iontronic devices for localized chemotherapy. These devices enable precise and continuous delivery of anti-cancer agents, and therefore, very potent tumor killing properties.
We demonstrate their effectiveness in two ways: i) electrically controlled chemotherapy and ii) releasing potent chemotherapeutics from a hydrogel with an electric trigger. Iontronic chemotherapy was able to stop tumor growth of brain tumors grown in an embryonic avian model. We currently test a wireless iontronic implant in freely moving rats with orthotopic tumors in their brain and monitor the tumor size with MRI.
For using even more potent drugs with efficiencies in the picomolar range, we use a click-to-release mechanism to release drugs from hydrogels, and demonstrate the system with pancreatic cancer cells. This system allows tight control over the release of highly potent therapeutics on demand, ensuring high toxicity specifically towards tumor cells but a non-toxic state when the gel is not activated.
The research has been funded by the EIC Pathfinder "bioSWITCH": #101099963 and BioTechMed Graz (Young Research Groups Grant)
nanoGe is a prestigious brand of successful science conferences that are developed along the year in different areas of the world since 2009. Our worldwide conferences cover cutting-edge materials topics like perovskite solar cells, photovoltaics, optoelectronics, solar fuel conversion, surface science, catalysis and two-dimensional materials, among many others.
Previously nanoGe Spring Meeting (NSM) and nanoGe Fall Meeting (NFM), MATSUS is a multiple symposia conference focused on a broad set of topics of advanced materials preparation, their fundamental properties, and their applications, in fields such as renewable energy, photovoltaics, lighting, semiconductor quantum dots, 2-D materials synthesis, charge carriers dynamics, microscopy and spectroscopy semiconductors fundamentals, etc.
International Conference on Hybrid and Organic Photovoltaics
International Conference on Hybrid and Organic Photovoltaics (HOPV) is celebrated yearly in May. The main topics are the development, function and modeling of materials and devices for hybrid and organic solar cells. The field is now dominated by perovskite solar cells but also other hybrid technologies, as organic solar cells, quantum dot solar cells, and dye-sensitized solar cells and their integration into devices for photoelectrochemical solar fuel production.
Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics
The main topics of the Asia-Pacific International Conference on Perovskite, Organic Photovoltaics and Optoelectronics (IPEROP) are discussed every year in Asia-Pacific for gathering the recent advances in the fields of material preparation, modeling and fabrication of perovskite and hybrid and organic materials. Photovoltaic devices are analyzed from fundamental physics and materials properties to a broad set of applications. The conference also covers the developments of perovskite optoelectronics, including light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.
The International Conference on Perovskite Thin Film Photovoltaics Perovskite Photonics and Optoelectronics (NIPHO) is the best place to hear the latest developments in perovskite solar cells as well as on recent advances in the fields of perovskite light-emitting diodes, lasers, optical devices, nanophotonics, nonlinear optical properties, colloidal nanostructures, photophysics and light-matter coupling.